The Pfizer logo is pictured at their building in the Manhattan borough of New York October 29, 2015. Botox maker Allergan Plc and Pfizer Inc on Thursday said they were in early, friendly talks to create the world's largest drugmaker and potentially set up Pfizer to take advantage of Ireland's lower tax rates. Both New York-based Pfizer and Dublin-based Allergan said no agreement has been reached and declined to discuss any terms. REUTERS/Carlo Allegri