Otsuka Holdings' President and CEO Tatsuo Higuchi speaks next to his company's Pocari Sweat sports drink during a news conference at the Tokyo Stock Exchange in Tokyo December 15, 2010. Shares of Otsuka Holdings posted modest gains in their debut on Wednesday after the company priced its $2.4 billion IPO conservatively to offset investor worries about future competition for its mainstay schizophrenia drug. REUTERS/Toru Hanai (JAPAN - Tags: BUSINESS HEALTH)