Parkinson's patient Jim Coppula smiles after working out in the ring as Ron Addison (R) awaits his turn during their Rock Steady Boxing class in Costa Mesa, California September 16, 2013. According to the Parkinson's Disease Foundation, research has shown that exercise can transiently increase the levels of dopamine in the brain, which is significantly reduced in Parkinson's disease. The club, whose headquarters is in Indianapolis, was started in 2006 and has 15 affiliates in six U.S. States, and one in Australia. Picture taken September 16, 2013. REUTERS/Mike Blake (UNITED STATES - Tags: HEALTH SOCIETY)